Starting a weight loss journey with medications like Ozempic or Mounjaro is exciting, but the “adjustment period” can be daunting. Most patients experience some form of gastrointestinal (GI) discomfort in the first few weeks.
At MyDoctor, we prioritize patient comfort as much as weight loss. Here is our medical guide to managing side effects:
Common Side Effects
Most symptoms—nausea, bloating, and occasional constipation—are signs that the medication is working to slow your digestion. These typically peak 24–48 hours after your dose and subside as your body adapts.
Strategies for Relief
- The “Slow and Low” Titration: We never start you on a maximum dose. We gradually increase your dosage over several months to allow your gut to build tolerance.
- Hydration is Non-Negotiable: GLP-1s can reduce your thirst cue. Drinking water with electrolytes helps prevent the headaches often mistaken for medication side effects.
- Prioritize Protein: “Muscle wasting” can occur if you eat too little. Focus on lean proteins (chicken, fish, tofu) to protect your metabolism.
- Eat Small, Frequent Meals: Since your stomach empties slower, large meals will make you feel uncomfortably full. Think “grazing” rather than “feasting.”
When to call MyDoctor: If you experience severe, persistent abdominal pain or vomiting, contact us immediately. While rare, these can be signs of more serious issues like pancreatitis.